Glas has developed a pod-based ENDS device enabled with age-verification technology. The E-Cigarette is locked when purchased and the user is required to register the device and age verify before it can be activated. The E-Liquid in the ENDS contains either 30 or 50 mg/ml of nicotine and is available in tobacco, menthol, or flavored varieties. The excess lifetime cancer risks (ELCR) of the Glas products were calculated taking into consideration of the HPHCs collected under intense vaping conditions and the flavor ingredients in the various products. A conservative approach of 100% flavor transfer was used. Adjusted Inhalation Unit Risk (IUR) values were used for constituents with known carcinogenicity. A default IUR value of 1.5 µg/day was used for Toxicity Tier IV constituents when no carcinogenicity data was available. On average, Glas products’ ELCR is 70% less than the currently FDA authorized Marketing Granted Order ENDS products and less than 0.66% of conventional cigarettes as represented by the Kentucky 1R6F reference cigarette. These analyses indicate that the Glas pod-based age gated E-Cigarettes have an ELCR meaningfully less than currently authorized products and significantly less than conventional cigarettes.