Abstract: The Glas G2 ENDS is a temperature-regulated nicotine salt pre-filled disposable pod connected system with two power settings designed to minimize the combustion byproducts across a range of operating environments, with age-gating technology. Seven different Glas flavors (three tobacco, two menthol, two non-characterizing; 50 mg/ml nicotine) were analyzed for HPHCs and compared with four market leading pod-based products in the ENDS category with similar stated nicotine strengths (Juul Classic Menthol 5%, Juul Virginia Tobacco 5%, myblu Intense Tobacco Chill 4%, and NJOY Ace Menthol 5.5%). All products were vaped under non-intense CRM No. 81 vaping regime. The aerosol HPHC values were converted to per mL e-liquid consumed for comparison. In case of non-detectable values, the level of quantitation (LOQ) values was used for comparative analysis. A comparative analysis of aerosol HPHC analysis of the Glas test articles vaped at ECO and STD power settings with minimum and maximum aerosol HPHC of combined values of all comparator products was conducted. An analysis of glycol impurities, nicotine minor alkaloids and degradation products, carbonyl compounds, volatile organic compounds, and ester compounds were significantly higher in the comparator products vs. the Glas products. This comparative HPHC analysis demonstrated that Glas e-liquids in combination testing with the Glas G2 device with two power settings yielded lower HPHCs compared to market leading pod-based nicotine delivery ENDS products.

Manoj Misra, Ed Carmines, Lise Fraissinet, Chemular Inc, Hudson MI, USA

Affiliations: Chemular, Inc, Hudson, MI, USA